Surface functionalisation of diatoms with dopamine modified iron-oxide nanoparticles: toward magnetically guided drug microcarriers with biologically derived morphologies

Dusan Losic; Yang Yu; Moom Sinn Aw; Spomenka Simovic; Benjamin Thierry; Jonas Addai-Mensah

doi:10.1039/c0cc01305f

Surface functionalisation of diatoms with dopamine modified iron-oxide nanoparticles: toward magnetically guided drug microcarriers with biologically derived morphologies

Chem Commun (Camb). 2010 Sep 14;46(34):6323-5. doi: 10.1039/c0cc01305f. Epub 2010 Aug 2.

Authors

Dusan Losic¹, Yang Yu, Moom Sinn Aw, Spomenka Simovic, Benjamin Thierry, Jonas Addai-Mensah

Affiliation

¹ Ian Wark Research Institute, University of South Australia, Mawson Lakes, SA 5095, Adelaide, Australia. dusan.losic@unisa.edu.au

PMID: 20676447
DOI: 10.1039/c0cc01305f

Abstract

Diatom silica microcapsules prepared by purification of diatomaceous earth (DE) were functionalised by dopamine modified iron-oxide nanoparticles, in order to introduce diatoms with magnetic properties. The application of magnetised diatoms as magnetically guided drug delivery microcarriers has been demonstrated.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Dopamine / chemistry*
Drug Carriers / chemistry*
Drug Delivery Systems
Ferrosoferric Oxide / chemistry*
Magnetics*
Nanoparticles / chemistry*
Particle Size
Pharmaceutical Preparations / chemistry*
Silicon Dioxide / chemistry*
Surface Properties

Substances

Drug Carriers
Pharmaceutical Preparations
Silicon Dioxide
Dopamine
Ferrosoferric Oxide