Anesthesia complications during scheduled cesarean delivery for morbidly obese women

Am J Obstet Gynecol. 2010 Sep;203(3):276.e1-5. doi: 10.1016/j.ajog.2010.06.022. Epub 2010 Jul 31.

Abstract

Objective: We sought to estimate the morbidity associated with regional anesthesia in morbidly obese women undergoing scheduled cesarean delivery.

Study design: This was a retrospective cohort study of women undergoing elective scheduled cesarean delivery from September 2004 through December 2008.

Results: A total of 142 morbidly obese, 251 overweight and obese, and 185 normal-weight women met inclusion criteria. Differences between groups were identified regarding: complicated placement (5.6%, 2.8%, and 0%, respectively; P = .007), failure to establish (2%, 0%, and 0%, respectively; P = .047), and insufficient duration (4%, 0%, and 0%, respectively; P = .02) of regional anesthesia. The groups differed in the frequency of general anesthesia (6%, 0%, and 0%, respectively; P = .003), intraoperative hypotension (3%, 0%, and 0%, respectively; P = .01), and overall anesthetic complications (8.4%, 0%, and 0%, respectively; P < .0001). Prepregnancy body mass index > or = 40 kg/m(2) (receiver operating characteristic area under the curve, 0.856; positive likelihood ratio, 4.0) and delivery body mass index > or = 45 kg/m(2) (receiver operating characteristic area under the curve, 0.877; positive likelihood ratio, 4.1) were predictive of anesthetic complications.

Conclusion: Morbidly obese women have significant risk for anesthesia complications during cesarean delivery.

MeSH terms

  • Analgesics / therapeutic use
  • Anesthesia, Conduction / adverse effects*
  • Anesthesia, General / adverse effects*
  • Body Mass Index
  • Cesarean Section*
  • Cohort Studies
  • Drug Utilization
  • Female
  • Humans
  • Hypotension / etiology
  • Intraoperative Complications
  • Ketamine / therapeutic use
  • Likelihood Functions
  • Obesity, Morbid / complications*
  • Post-Dural Puncture Headache / etiology
  • Pregnancy
  • ROC Curve
  • Retrospective Studies
  • Time Factors

Substances

  • Analgesics
  • Ketamine