Acanthamoeba meningoencephalitis in an immunocompetent patient: an autopsy case report

Rajesh Reddy; Mudumba Vijayasaradhi; Megha S Uppin; Sundaram Challa; Afshan Jabeen; Rupam Borghain

doi:10.1111/j.1440-1789.2010.01151.x

Acanthamoeba meningoencephalitis in an immunocompetent patient: an autopsy case report

Neuropathology. 2011 Apr;31(2):183-7. doi: 10.1111/j.1440-1789.2010.01151.x.

Authors

Rajesh Reddy¹, Mudumba Vijayasaradhi, Megha S Uppin, Sundaram Challa, Afshan Jabeen, Rupam Borghain

Affiliation

¹ Department of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, India.

PMID: 20667014
DOI: 10.1111/j.1440-1789.2010.01151.x

Abstract

Chronic granulomatous CNS infections may be caused by tuberculosis, fungi and rarely by free-living amoeba, especially in immunocompromised individuals. We report a rare, fatal case of granulomatous amoebic encephalitis in an immunocompetent patient mimicking CNS tuberculosis, and review the imageological features and diagnostic tests.

Publication types

Case Reports

MeSH terms

Acanthamoeba / physiology*
Adult
Amebiasis / complications*
Amebiasis / pathology*
Autopsy
Central Nervous System Protozoal Infections / microbiology*
Central Nervous System Protozoal Infections / pathology*
Diagnosis, Differential
Fatal Outcome
Humans
Male
Tuberculosis, Central Nervous System / pathology