Aquilarin A, a new benzenoid derivative from the fresh stem of Aquilaria sinensis

Qing-Huang Wang; Ke Peng; Le-He Tan; Hao-Fu Dai

doi:10.3390/molecules15064011

Aquilarin A, a new benzenoid derivative from the fresh stem of Aquilaria sinensis

Molecules. 2010 Jun 1;15(6):4011-6. doi: 10.3390/molecules15064011.

Authors

Qing-Huang Wang¹, Ke Peng, Le-He Tan, Hao-Fu Dai

Affiliation

¹ National Center of Important Tropical Crops Engineering and Technology Research, Chinese Academy of Tropical Agricultural Sciences, Danzhou 571737, Hainan, China. wqh3687@163.com

Abstract

Chemical investigation of the EtOH extract of the fresh stem of Aquilaria sinensis collected in Hainan Province of China resulted in the isolation of a new benzenoid, named aquilarin A (1), together with two known compounds balanophonin (2) and (+)-lariciresinol (3). Their structures were elucidated by a study of their physical and spectral data. Compounds 2 and 3 exhibited cytotoxicity against SGC-7901 and SMMC-7721 cell lines.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antinematodal Agents / chemistry
Antinematodal Agents / pharmacology
Benzene Derivatives / chemistry*
Benzene Derivatives / pharmacology
Cell Line, Tumor
Furans / chemistry
Humans
Lignans / chemistry
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Stems / chemistry*
Thymelaeaceae / chemistry*

Substances

Antinematodal Agents
Benzene Derivatives
Furans
Lignans
lariciresinol