Platinum-catalyzed hydrative cyclization of 1,6-diynes for the synthesis of 3,5-substituted conjugated cyclohexenones

Chen Zhang; Jian-Feng Qi; Dong-Mei Cui; Qian Wang; Xiu-Li Wang

doi:10.3390/molecules15075045

Platinum-catalyzed hydrative cyclization of 1,6-diynes for the synthesis of 3,5-substituted conjugated cyclohexenones

Molecules. 2010 Jul 23;15(7):5045-52. doi: 10.3390/molecules15075045.

Authors

Chen Zhang¹, Jian-Feng Qi, Dong-Mei Cui, Qian Wang, Xiu-Li Wang

Affiliation

¹ School of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Abstract

We have developed a Pt(COD)Cl(2)-catalyzed hydrative cyclization of 1,6-diynes leading to the formation of functionalized cyclohexenones in good yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Cyclization
Diynes / chemistry*
Hexanones / chemical synthesis*
Platinum / chemistry*

Substances

Diynes
Hexanones
Platinum