Mosquitocidal triterpenes from the stem of Duranta repens

Pharm Biol. 2010 Mar;48(3):264-8. doi: 10.3109/13880200903096570.

Abstract

Two triterpenes, beta-amyrin and 12-oleanene 3beta, 21beta-diol, were isolated as a mixture from the chloroform soluble fraction of an ethanol extract of Duranta repens Linn (Verbenaceae) stem. The structures of the two compounds were confirmed by analysis of their IR, (1)H-NMR, (13)C-NMR and LC-MS spectral data. The mixture of beta-amyrin and 12-oleanene 3beta, 21beta-diol (compound 1) was highly effective against the larvae of the mosquito, Culex quinquefasciatus Say (Diptera: Culicidae), as a mosquitocide.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatography, High Pressure Liquid
  • Culex* / growth & development
  • Insecticide Resistance
  • Insecticides / analysis
  • Insecticides / chemistry*
  • Insecticides / isolation & purification
  • Larva
  • Lethal Dose 50
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Structure
  • Mosquito Control
  • Oleanolic Acid / analogs & derivatives
  • Oleanolic Acid / analysis
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification
  • Plant Extracts / chemistry
  • Plant Stems / chemistry
  • Reproducibility of Results
  • Spectrophotometry, Infrared
  • Time Factors
  • Triterpenes / analysis
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification
  • Verbenaceae / chemistry*

Substances

  • 12-oleanene-3beta,21beta-diol
  • Insecticides
  • Plant Extracts
  • Triterpenes
  • Oleanolic Acid
  • beta-amyrin