No interference of the 1,3-β-D-glucan containing nutritional supplement ImunixX with the 1,3-β-D-glucan serum test

Mycoses. 2011 Sep;54(5):e352-3. doi: 10.1111/j.1439-0507.2010.01922.x. Epub 2010 Jul 19.

Abstract

The detection of 1,3-β-D-glucan serum levels may permit establishing the diagnosis of invasive fungal infections more early. We tested in six healthy volunteers whether the intake of a 1,3-β-D-glucan-containing nutritional supplement leads to false-positive 1,3-β-D-glucan levels. All levels were negative, even in two different dosing regimens.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Diet / methods*
  • False Positive Reactions
  • Female
  • Fungemia / diagnosis*
  • Humans
  • Immunoassay / methods
  • Male
  • Mycology / methods*
  • Proteoglycans
  • Serum / chemistry*
  • beta-Glucans / blood*

Substances

  • Proteoglycans
  • beta-Glucans
  • polysaccharide-K