RPPanalyzer: Analysis of reverse-phase protein array data

Bioinformatics. 2010 Sep 1;26(17):2202-3. doi: 10.1093/bioinformatics/btq347. Epub 2010 Jul 15.

Abstract

Summary: RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data. Implemented plotting functions permit a quality control by monitoring data distribution and signal validity. Finally, the data can be visualized in heatmaps, boxplots, time course plots and correlation plots. RPPanalyzer is a flexible tool and tolerates a huge variety of different experimental designs.

Availability: The RPPAanalyzer is open source and freely available as an R-Package on the CRAN platform http://cran.r-project.org/.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Protein Array Analysis / methods*
  • Proteomics / methods
  • Software*