Anti-allergic drugs and the Annexin-A1 system

Samia Yazid; Samir S Ayoub; Egle Solito; Simon McArthur; Phuong Vo; Neil Dufton; Roderick J Flower

doi:10.1016/s1734-1140(10)70307-8

Anti-allergic drugs and the Annexin-A1 system

Pharmacol Rep. 2010 May-Jun;62(3):511-7. doi: 10.1016/s1734-1140(10)70307-8.

Authors

Samia Yazid¹, Samir S Ayoub, Egle Solito, Simon McArthur, Phuong Vo, Neil Dufton, Roderick J Flower

Affiliation

¹ Biochemical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.

PMID: 20631415
DOI: 10.1016/s1734-1140(10)70307-8

Abstract

This paper, which was presented at the 17th JMRC 'John Robert Vane Memorial' Symposium, describes some recent work from the authors' laboratory that provides a tentative explanation for the anti-inflammatory effects produced by the cromoglycate-like anti-allergic drugs. Some of the implications of this finding are discussed.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Annexin A1 / metabolism*
Anti-Allergic Agents / metabolism
Anti-Allergic Agents / pharmacology*
Cromolyn Sodium / metabolism
Cromolyn Sodium / pharmacology
Humans
Inflammation / metabolism
Mast Cells / metabolism
U937 Cells

Substances

Annexin A1
Anti-Allergic Agents
Cromolyn Sodium

Abstract

Publication types

MeSH terms

Substances

Grants and funding