An eco-friendly N-sulfonylation of amines using stable and reusable Zn-Al-hydrotalcite solid base catalyst under ultrasound irradiation

M Mokhtar; T S Saleh; N S Ahmed; S A Al-Thabaiti; R A Al-Shareef

doi:10.1016/j.ultsonch.2010.05.001

An eco-friendly N-sulfonylation of amines using stable and reusable Zn-Al-hydrotalcite solid base catalyst under ultrasound irradiation

Ultrason Sonochem. 2011 Jan;18(1):172-6. doi: 10.1016/j.ultsonch.2010.05.001. Epub 2010 May 10.

Authors

M Mokhtar¹, T S Saleh, N S Ahmed, S A Al-Thabaiti, R A Al-Shareef

Affiliation

¹ Chemistry Department, Faculty of Science, King Abdulaziz University, 21589 Jeddah, P.O. Box 80203, Saudi Arabia.

PMID: 20627793
DOI: 10.1016/j.ultsonch.2010.05.001

Abstract

Synthetic nanosized Zn-Al-hydrotalcite (Zn-Al-HT) with 20 nm crystallite size and 61 m(2)/g BET-surface area is found to be a mild and efficient catalyst for N-sulfonylation of amines in quantitative yields under ultrasound irradiation. Exclusive synthesis of sulfonamides, using Zn-Al-HT, under ultrasound irradiation, was realized by compatible basic sites of catalyst used. The products were isolated after simple work-up in high yields and purity.

MeSH terms

Aluminum / chemistry*
Aluminum Hydroxide / chemistry*
Amines / chemistry*
Catalysis
Magnesium Hydroxide / chemistry*
Nanoparticles / chemistry
Particle Size
Sulfonic Acids / chemistry*
Surface Properties
Ultrasonics*
Zinc / chemistry*

Substances

Amines
Sulfonic Acids
hydrotalcite
Aluminum Hydroxide
Aluminum
Zinc
Magnesium Hydroxide