HIF-2alpha--a mediator of osteoarthritis?

Cell Res. 2010 Sep;20(9):977-9. doi: 10.1038/cr.2010.99. Epub 2010 Jul 13.

Author

Christopher L Murphy¹

Affiliation

¹ The Kennedy Institute of Rheumatology, Imperial College London, 65 Aspenlea Road, London W6 8LH, England, United Kingdom. c.murphy@imperial.ac.uk

PMID: 20625379
DOI: 10.1038/cr.2010.99

No abstract available

MeSH terms

2-Methoxyestradiol
Animals
Basic Helix-Loop-Helix Transcription Factors / genetics
Basic Helix-Loop-Helix Transcription Factors / metabolism*
Chondrocytes / metabolism
Collagen Type II / metabolism
Estradiol / analogs & derivatives
Estradiol / pharmacology
Humans
Mice
Osteoarthritis / metabolism*
Procollagen-Proline Dioxygenase / metabolism

Substances

Basic Helix-Loop-Helix Transcription Factors
Col2a1 protein, mouse
Collagen Type II
endothelial PAS domain-containing protein 1
Estradiol
2-Methoxyestradiol
PHD1 protein, mouse
Procollagen-Proline Dioxygenase