Abstract
Infusion of 1000 ml of 6% hydroxyethylstarch (HES) of the third generation 130/0.42 or crystalloid solutions was conducted to patients before performance of operation on abdominal cavity organs using epidural anesthesia. While HES application the average arterial pressure after induction into anesthesia was less pronounced and concentration of C-reactive protein on the third postoperative day was lesser. It is concluded, that HES 130/0.42 secures the hemodynamic indices stability and reduction of systemic inflammatory reaction severity in the patients and do not influence hemostasis and renal function.
Publication types
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Clinical Trial
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English Abstract
MeSH terms
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Anesthesia, Epidural*
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Blood Pressure / drug effects
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C-Reactive Protein / analysis
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Digestive System Surgical Procedures / methods*
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Female
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Hemodynamics / drug effects*
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Humans
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Hydroxyethyl Starch Derivatives / administration & dosage
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Hydroxyethyl Starch Derivatives / pharmacology*
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Immunoglobulin M / analysis
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Infusions, Intravenous
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Kidney / drug effects
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Kidney Function Tests
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Male
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Middle Aged
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Plasma Substitutes / administration & dosage
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Plasma Substitutes / pharmacology*
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Postoperative Complications / epidemiology
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Postoperative Complications / immunology
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Postoperative Complications / prevention & control
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Postoperative Period
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Preoperative Care
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Systemic Inflammatory Response Syndrome / epidemiology
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Systemic Inflammatory Response Syndrome / immunology
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Systemic Inflammatory Response Syndrome / prevention & control
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Treatment Outcome
Substances
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Hydroxyethyl Starch Derivatives
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Immunoglobulin M
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Plasma Substitutes
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C-Reactive Protein