Abstract
We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Drug Carriers / chemistry
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Hydrogen-Ion Concentration
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Mice
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Micelles*
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Microscopy, Fluorescence
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Neoplasms / diagnosis*
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Neoplasms / drug therapy*
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Photochemotherapy*
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Photosensitizing Agents / administration & dosage*
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Polymers / chemistry*
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Protoporphyrins / administration & dosage*
Substances
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Drug Carriers
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Micelles
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Photosensitizing Agents
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Polymers
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Protoporphyrins
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protoporphyrin IX