Bioactive xanthones from the stems of Cratoxylum formosum ssp. pruniflorum

Ying-hui Duan; Yi Dai; Guang-hui Wang; Xue Zhang; Hai-feng Chen; Jie-bo Chen; Xin-sheng Yao; Xiao-kun Zhang

doi:10.1021/np1001797

Bioactive xanthones from the stems of Cratoxylum formosum ssp. pruniflorum

J Nat Prod. 2010 Jul 23;73(7):1283-7. doi: 10.1021/np1001797.

Authors

Ying-hui Duan¹, Yi Dai, Guang-hui Wang, Xue Zhang, Hai-feng Chen, Jie-bo Chen, Xin-sheng Yao, Xiao-kun Zhang

Affiliation

¹ College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.

PMID: 20608716
DOI: 10.1021/np1001797

Abstract

Six new compounds, pruniflorones M-R (1-6), together with 19 known compounds (7-25) were isolated from the stems of Cratoxylum formosum ssp. pruniflorum. The structures of the new compounds were established on the basis of extensive spectroscopic data interpretation. In addition, their RXRalpha transcriptional activities were evaluated using an in vitro assay.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chlorocebus aethiops
Clusiaceae / chemistry*
Drugs, Chinese Herbal / chemistry
Drugs, Chinese Herbal / isolation & purification*
Drugs, Chinese Herbal / pharmacology*
Nuclear Magnetic Resonance, Biomolecular
Plant Stems / chemistry
Retinoid X Receptor alpha / drug effects*
Retinoid X Receptor alpha / metabolism
Xanthones / chemistry
Xanthones / isolation & purification*
Xanthones / pharmacology*

Substances

Drugs, Chinese Herbal
Retinoid X Receptor alpha
Xanthones