Emergence of Klebsiella pneumoniae carrying bla(VIM) and bla(KPC) genes

G Meletis; E Tzampaz; E Protonotariou; D Sofianou

Emergence of Klebsiella pneumoniae carrying bla(VIM) and bla(KPC) genes

Hippokratia. 2010 Apr;14(2):139-40.

Authors

G Meletis¹, E Tzampaz, E Protonotariou, D Sofianou

Affiliation

¹ Department of Clinical Microbiology, Hippokratio General Hospital, Thessaloniki, Greece.

PMID: 20596274
PMCID: PMC2895282

Abstract

A Klebsiella pneumoniae clinical isolate resistant to imipenem was recovered from a wound sample. The patient, a 57-year-old man, underwent a surgical resection of small bowel and sigmoid colon and was treated with multiple courses of antimicrobials. PCR analysis revealed that the clinical isolate was carrying simultaneously bla(VIM-1), bla(KPC-2), bla(SHV) and bla(TEM) genes. The concomitant presence of these genes is alarming and poses therapeutic as well as infection control problems.

Keywords: KPC-2; Klebsiella pneumoniae; SHV; TEM; VIM-1; carbapenemases; β-lactamases.

Publication types

Case Reports