Hold on tightly, let go lightly: myosin functions at adherens junctions

Nat Cell Biol. 2010 Jul;12(7):633-5. doi: 10.1038/ncb0710-633.

Abstract

Adherens junctions, the sites of cadherin-dependent cell-cell adhesion, are also important for dynamic tension sensing, force transduction and signalling. Different myosin motors contribute to adherens junction assembly and versatility in distinct ways.

Publication types

  • Comment
  • News

MeSH terms

  • Adherens Junctions / metabolism*
  • Cadherins / metabolism
  • Cell Adhesion / physiology
  • Cell Line, Tumor
  • Chromatids / metabolism
  • Humans
  • Kinetochores / metabolism
  • Models, Biological
  • Nonmuscle Myosin Type IIA / metabolism*
  • Nonmuscle Myosin Type IIB / metabolism*

Substances

  • Cadherins
  • Nonmuscle Myosin Type IIA
  • Nonmuscle Myosin Type IIB