Combining host-guest systems with nonfouling material for the fabrication of a biosurface: toward nearly complete and reversible resistance of cytochrome c

Pengbo Wan; Yueyue Chen; Yibo Xing; Lifeng Chi; Xi Zhang

doi:10.1021/la102336a

Combining host-guest systems with nonfouling material for the fabrication of a biosurface: toward nearly complete and reversible resistance of cytochrome c

Langmuir. 2010 Aug 3;26(15):12515-7. doi: 10.1021/la102336a.

Authors

Pengbo Wan¹, Yueyue Chen, Yibo Xing, Lifeng Chi, Xi Zhang

Affiliation

¹ Key Lab of Organic Optoelectronics & Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing 100084, PR China.

PMID: 20590109
DOI: 10.1021/la102336a

Abstract

In this letter, a pH-responsive reactivated biointerface is fabricated using an inclusion reaction between an azobenzene-containing self-assembled monolayer and pH-responsive poly(ethylene glycol)-block-poly(acrylic acid) grafted with cyclodextrins. The pH-responsive interface can be switched between an extended state and a relaxed state for the reversible resistance of cytochrome c adsorption completely in cooperation with protein-resistant poly(ethylene glycol).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acrylates / chemistry*
Azo Compounds / chemistry
Cytochromes c / chemistry*
Hydrogen-Ion Concentration
Models, Biological
Polyethylene Glycols / chemistry*
Polymers / chemistry*

Substances

Acrylates
Azo Compounds
Polymers
Polyethylene Glycols
Cytochromes c
azobenzene