Novel heteronuclear ruthenium-copper coordination compounds as efficient DNA-cleaving agents

Chem Commun (Camb). 2010 May 28;46(20):3568-70. doi: 10.1039/c000077a. Epub 2010 Mar 22.

Abstract

The DNA-cleavage ability of novel bifunctional heterobimetallic copper-ruthenium complexes is demonstrated by using gel electrophoresis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Copper / chemistry*
  • DNA / drug effects*
  • DNA Cleavage*
  • Molecular Structure
  • Organometallic Compounds / chemistry
  • Organometallic Compounds / pharmacology*
  • Ruthenium / chemistry*

Substances

  • Organometallic Compounds
  • Copper
  • Ruthenium
  • DNA