[Studies on the chemical constituents of extract with water from Forsythia suspensa]

Zhong Yao Cai. 2010 Feb;33(2):220-1.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents of the extract with water from Forsythia suspensa.

Methods: The compounds were isolated and repeatedly purified on TLC, silica gel column chromatograph, gel column chromatography, and preparative HPLC, and the structures were elucidated by physico-chemical properties and NMR.

Results: Eight compounds were obtained and elucidated as stearic acid(I), ursolic acid(II),p-hydroxyphenyl acetic acid(III),3-(4-ehtoxoy-3-hydroxyphenyl)acrylic acid(IV),isolariciresinol(V), epipinoresinol-4-O-beta-D-glucoside(VI),(+)-epipinoresionl(VII),(+)-pinoresinol(VIII).

Conclusion: Compound III is isolated from this genus for the first time.

MeSH terms

  • Drugs, Chinese Herbal / chemistry*
  • Forsythia / chemistry*
  • Fruit / chemistry
  • Lignin / chemistry
  • Lignin / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Naphthols / chemistry
  • Naphthols / isolation & purification
  • Phenylacetates / chemistry
  • Phenylacetates / isolation & purification*
  • Plant Extracts / chemistry
  • Plants, Medicinal / chemistry*
  • Stearic Acids / chemistry
  • Stearic Acids / isolation & purification*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification
  • Ursolic Acid
  • Water / chemistry

Substances

  • Drugs, Chinese Herbal
  • Naphthols
  • Phenylacetates
  • Plant Extracts
  • Stearic Acids
  • Triterpenes
  • Water
  • 4-hydroxyphenylacetic acid
  • stearic acid
  • isolariciresinol
  • Lignin