Human astrovirus infection in a patient with new-onset celiac disease

Saskia L Smits; Marije van Leeuwen; Annemiek A van der Eijk; Pieter L A Fraaij; Johanna C Escher; James H Simon; Albert D M E Osterhaus

doi:10.1128/JCM.01164-10

Human astrovirus infection in a patient with new-onset celiac disease

J Clin Microbiol. 2010 Sep;48(9):3416-8. doi: 10.1128/JCM.01164-10. Epub 2010 Jun 23.

Authors

Saskia L Smits¹, Marije van Leeuwen, Annemiek A van der Eijk, Pieter L A Fraaij, Johanna C Escher, James H Simon, Albert D M E Osterhaus

Affiliation

¹ ViroClinics BioSciences, Erasmus Medical Center, P.O. Box 2040, 3000 CA Rotterdam, the Netherlands.

Abstract

Many diseases with unknown etiology may be caused by unidentified viruses. Sequence-independent amplification revealed a new astrovirus, similar to VA1, in a 4-year-old male diagnosed with celiac disease. This expands the geographic range of this virus to include Europe and may associate astrovirus infection with the onset of celiac disease.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Astroviridae Infections / complications*
Astroviridae Infections / diagnosis*
Astroviridae Infections / virology
Celiac Disease / complications*
Celiac Disease / virology*
Child, Preschool
Humans
Male
Mamastrovirus / isolation & purification*
Netherlands