Abstract
Substitution of a pyridyl for the hydroxyphenyl moiety in the Green Fluorescent Protein analog p-hydroxybenzylidene-dimethylimidiazolinone produces a chromophore which "turns on" fluorescence in the presence of Zn(2+) or Cd(2+) ions. Such a phenomenon provides "proof of principle" for using GFP chromophores in a variety of sensing applications.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Benzyl Compounds / chemistry*
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Cadmium / chemistry
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Coordination Complexes / chemical synthesis
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Coordination Complexes / chemistry*
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Green Fluorescent Proteins / chemistry
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Imidazolines / chemistry*
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Ligands
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Molecular Conformation
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Spectrometry, Fluorescence
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Zinc / chemistry
Substances
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Benzyl Compounds
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Coordination Complexes
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Imidazolines
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Ligands
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p-hydroxybenzylidenedimethylimidazolinone
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Cadmium
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Green Fluorescent Proteins
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Zinc