Preventing infective complications relating to induced abortion

Best Pract Res Clin Obstet Gynaecol. 2010 Aug;24(4):539-49. doi: 10.1016/j.bpobgyn.2010.03.005. Epub 2010 Jun 12.

Abstract

Infective complications following induced abortions are still a common cause of morbidity and mortality. This review focusses on defining the strategies to improve care of women seeking an induced abortion and to reduce infective complications. We have considered the evidence for screening and cost-effectiveness for antibiotic prophylaxis. Current evidence suggests that treating all women with prophylactic antibiotics in preference to screening and treating is the most cost-effective way of reducing infective complications following induced abortions. The final strategy to prevent infective complications should be individualized for each region/area depending on the prevalence of organisms causing pelvic infections and the resources available.

Publication types

  • Review

MeSH terms

  • Abortion, Induced / adverse effects*
  • Abortion, Induced / methods
  • Adolescent
  • Adult
  • Antibiotic Prophylaxis / economics
  • Antibiotic Prophylaxis / methods*
  • Azithromycin / economics
  • Azithromycin / therapeutic use
  • Cost-Benefit Analysis
  • Doxycycline / economics
  • Doxycycline / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Humans
  • Metronidazole / economics
  • Metronidazole / therapeutic use
  • Pelvic Inflammatory Disease / drug therapy
  • Pelvic Inflammatory Disease / etiology*
  • Postoperative Complications / prevention & control
  • Pregnancy
  • Sexually Transmitted Diseases, Bacterial / drug therapy
  • Young Adult

Substances

  • Metronidazole
  • Azithromycin
  • Doxycycline