Abstract
Continuous delivery of antiparkinsonian medication during a perioperative period is desirable to avoid 'off'-symptom complications in surgical patients with concomitant Parkinson's disease (PD). Fourteen PD patients undergoing surgery under general anesthesia were switched from oral dopaminergic medication to transdermally delivered 24-h rotigotine (median dose 12 mg/24 h) for the perioperative period. Rotigotine treatment was considered feasible by patients, their anesthesiologists and neurologists with good control of PD symptoms and easy switching and re-switching of PD medication.
Publication types
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Clinical Trial
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Multicenter Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Cutaneous
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Aged
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Aged, 80 and over
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Anesthesia, General
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Anesthesiology
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Attitude of Health Personnel
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Dopamine Agonists / administration & dosage*
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Dopamine Agonists / therapeutic use
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Feasibility Studies
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Female
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Humans
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Male
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Middle Aged
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Neurology
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Parkinson Disease / drug therapy*
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Parkinson Disease / psychology
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Parkinson Disease / surgery*
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Perioperative Care*
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Physicians / psychology
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Prospective Studies
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Tetrahydronaphthalenes / administration & dosage*
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Tetrahydronaphthalenes / therapeutic use
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Thiophenes / administration & dosage*
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Thiophenes / therapeutic use
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Treatment Outcome
Substances
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Dopamine Agonists
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Tetrahydronaphthalenes
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Thiophenes
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rotigotine