Objective: Exploration of a possible relationship between pramipexole and compulsive masturbation.
Methods: We present a case report.
Results: Given the temporal overlap between pramipexole prescription and its discontinuation, and the onset and cessation of the patient's hypersexual behavior, there appears to be a strong likelihood of association.
Conclusions: Like other dopamine agonists, pramipexole may precipitate compulsive behaviors, including hypersexual behavior in the form of compulsive masturbation.
Keywords: adverse effects; compulsive sexual behavior; dopamine agonists; hypersexual behavior; masturbation.