Abstract
A fast and highly efficient copper-catalyzed multicomponent synthesis of 1,4-dihydropyridines under microwave irradiation is described. The protocol utilizes mild reaction conditions with low catalytic loading, leading to high yields. This methodology provides us with biologically active 1,4-dihydropyridine library for medicinal chemistry applications.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Combinatorial Chemistry Techniques*
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Copper / chemistry*
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Crystallography, X-Ray
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Dihydropyridines / chemical synthesis*
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Dihydropyridines / chemistry
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Microwaves*
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Models, Molecular
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Molecular Structure
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Small Molecule Libraries
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Stereoisomerism
Substances
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Dihydropyridines
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Small Molecule Libraries
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Copper