Synthesis of Substituted N-[4(5-Methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-yl]benzamide/benzene Sulfonamides as Anti-Inflammatory and Anti-Cancer Agents

Madhavi Gangapuram; Kinfe K Redda

doi:10.1002/jhet.62

Synthesis of Substituted N-[4(5-Methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-yl]benzamide/benzene Sulfonamides as Anti-Inflammatory and Anti-Cancer Agents

J Heterocycl Chem. 2009 May 1;46(2):309-316. doi: 10.1002/jhet.62.

Authors

Madhavi Gangapuram¹, Kinfe K Redda

Affiliation

¹ College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, Florida 32307.

PMID: 20526413
PMCID: PMC2880475
DOI: 10.1002/jhet.62

Abstract

Fourteen novel substituted N-[4(5-methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-y1] benzamide/benzene sulfonamides (11a-n) were synthesized in fair to good yields via sodium borohydride reduction of the corresponding substituted N-(benzoylimino)-4-(5-methyl/5-phenyl-1,3,4-oxadiazol-2yl) pyridinium ylide (10a-n) in absolute ethanol.

Abstract

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