Transcriptomics and disease vector control

BMC Biol. 2010 May 7:8:52. doi: 10.1186/1741-7007-8-52.

Abstract

Next-generation sequencing can be used to compare transcriptomes under different conditions. A study in BMC Genomics applies this approach to investigating the effects of exposure to a range of xenobiotics on changes in gene expression in the larvae of Aedes aegypti, the mosquito vector of dengue fever.

Publication types

  • Review

MeSH terms

  • Aedes / drug effects*
  • Aedes / genetics
  • Aedes / metabolism
  • Animals
  • Disease Vectors*
  • Gene Expression Profiling / methods*
  • Gene Expression Regulation / drug effects*
  • Insect Control / methods*
  • Insecticide Resistance / genetics
  • Larva / drug effects
  • Larva / metabolism
  • Oligonucleotide Array Sequence Analysis / methods*
  • Sequence Analysis, DNA / methods
  • Xenobiotics / toxicity

Substances

  • Xenobiotics