Abstract
We showed herein the potent virucidal effect of soap and water solutions against both CCR5-tropic and CXCR4-tropic cell-free HIV-1 strains, and cytotoxicity for HIV-1-infected lymphocytes during short incubation durations, ranging from 30 seconds to 2 minutes. These observations indicate a rapid inhibitory effect of soap and water on viral infectivity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-HIV Agents / immunology
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Anti-HIV Agents / pharmacology
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Antiviral Agents / pharmacology
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CCR5 Receptor Antagonists
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Cell Survival / drug effects
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HIV Infections / immunology*
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HIV-1 / drug effects*
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Lymphocytes / drug effects
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Lymphocytes / immunology
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Lymphocytes / virology
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Receptors, CCR5 / physiology*
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Receptors, CXCR4 / antagonists & inhibitors
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Receptors, CXCR4 / physiology*
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Soaps / pharmacology*
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South Africa
Substances
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Anti-HIV Agents
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Antiviral Agents
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CCR5 Receptor Antagonists
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Receptors, CCR5
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Receptors, CXCR4
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Soaps