The current study examines the social information processing and coping styles (SIP) of overweight and average weight adolescents, and whether the associations between friendship quality and SIP differ for these two groups (N = 156, M age = 12.79). On the basis of height and weight assessments, overweight (n = 70) and average weight (n = 86) adolescents were identified. Participants reported on positive and conflictual qualities of their friendships, and their attributions, emotional reactions, and coping strategies in response to hypothetical negative peer events. Results revealed that for overweight adolescents, positive friendship quality was negatively associated with emotion-focused coping, and friendship conflict was positively associated with internal blame attributions, but the associations between these variables were not significant for average weight adolescents. Findings suggest that positive friendships may represent protective factors in the lives of overweight adolescents whereas highly conflictual friendships may increase risk.