Comparison between human and rat TMJ: anatomic and histopathologic features

Acta Cir Bras. 2010 Jun;25(3):290-3. doi: 10.1590/s0102-86502010000300012.

Abstract

Purpose: To describe and evaluate normal rat temporomandibular joints from anatomic and histopathologic point of view and make a comparison between this joint in rats and humans.

Methods: Twelve male adult Wistar rats (12 same side joints) were used in this procedure. The following anatomical structures were histologically evaluated in a qualitative fashion: condyle, disc, temporal bone, retrodiscal tissue and synovia. The macroscopical and microscopic study of the human TMJ was based on the current literature.

Results: The TMJ is surrounded by a thin capsule, consisting of fibrous tissue, and a synovial lining. The mandibular angle has a prominent shape. The glenoid fossa is flat, with no eminences. Histologically, the TMJ is composed of different tissues that comprise the mandibular head, mandibular fossa and fibrocartilaginous disc. A layer of hyaline cartilage covers the articulating cortical condyle and temporal bone.

Conclusion: Morphologically and histologically, the articular structure of rats is, on the whole, similar to that of humans. In these animals there is no articular eminence.

MeSH terms

  • Anatomy, Comparative
  • Animals
  • Humans
  • Male
  • Mandibular Condyle / anatomy & histology
  • Models, Animal
  • Rats
  • Rats, Wistar
  • Temporal Bone / anatomy & histology
  • Temporomandibular Joint / anatomy & histology*
  • Temporomandibular Joint / cytology*
  • Temporomandibular Joint Disc / anatomy & histology