Unprecedented tunable tetraazamacrocycles

Rose Haddoub; Mounia Touil; Jean-Manuel Raimundo; Olivier Siri

doi:10.1021/ol100793g

Unprecedented tunable tetraazamacrocycles

Org Lett. 2010 Jun 18;12(12):2722-5. doi: 10.1021/ol100793g.

Authors

Rose Haddoub¹, Mounia Touil, Jean-Manuel Raimundo, Olivier Siri

Affiliation

¹ Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), UPR 3118 CNRS Aix-Marseille Universite, Campus de Luminy, case 913, F-13288 Marseille, Cedex 09, France.

PMID: 20481643
DOI: 10.1021/ol100793g

Abstract

Novel nitrogen-bridged aza[1(4)]cyclophanes with fine-tuned cavities have been synthesized by nucleophilic aromatic substitution of 1,5-difluoro-2,4-dinitrobenzene with diaminobenzene derivatives.