Abstract
Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness, purging fire to eliminate toxin. Berberine is the main alkaloid of Coptis Chinensis, and, recent researches showed that berberine had the effect of anti-atherosclerosis. This paper reviewed the anti-atherosclerosis mechanism of berberine, which may be related to regulating lipids, anti-inflammation, decompression, reducing blood sugar, and inhibiting vascular smooth muscle cell proliferation.
MeSH terms
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Animals
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Anti-Inflammatory Agents / pharmacology
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Anti-Inflammatory Agents / therapeutic use
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Atherosclerosis / prevention & control*
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Berberine / pharmacology*
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Berberine / therapeutic use*
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Blood Glucose / drug effects
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Blood Pressure / drug effects
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Humans
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Hypolipidemic Agents / pharmacology
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Hypolipidemic Agents / therapeutic use
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Inflammation / prevention & control
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Lipid Metabolism / drug effects
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Lipids / blood
Substances
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Anti-Inflammatory Agents
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Blood Glucose
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Hypolipidemic Agents
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Lipids
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Berberine