[Long-term remission of malignant melanoma stage IV after antigen-specific immunotherapy]

Med Klin (Munich). 2010 Apr;105(4):273-5. doi: 10.1007/s00063-010-1041-7.
[Article in German]

Abstract

This case report describes the clinical course of a patient with progressing metastatic melanoma (M1a) under standard chemotherapy, followed by long-term partial remission of disease under treatment with experimental, specific immunotherapy. Detectable specific immune responses demonstrate the correlation between continued tumor regression and the administered specific immunotherapy.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antigens, Neoplasm / immunology*
  • Antineoplastic Combined Chemotherapy Protocols
  • CD4-Positive T-Lymphocytes / drug effects
  • CD4-Positive T-Lymphocytes / immunology
  • CD8-Positive T-Lymphocytes / drug effects
  • CD8-Positive T-Lymphocytes / immunology
  • Cancer Vaccines / therapeutic use*
  • Chemotherapy, Adjuvant
  • Disease Progression
  • Epitopes / immunology*
  • Female
  • Follow-Up Studies
  • Humans
  • Hypersensitivity, Delayed / immunology
  • Immunotherapy / methods*
  • Injections, Intradermal
  • Leg*
  • Lymphatic Metastasis / pathology
  • Melanoma / drug therapy*
  • Melanoma / immunology
  • Melanoma / pathology
  • Melanoma / surgery
  • Melanoma-Specific Antigens
  • Middle Aged
  • Neoplasm Proteins / immunology*
  • Neoplasm Staging
  • Palliative Care
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / immunology
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery
  • Survivors*

Substances

  • Antigens, Neoplasm
  • Cancer Vaccines
  • Epitopes
  • Melanoma-Specific Antigens
  • Neoplasm Proteins