[Ru(III)(edta)(H(2)O)](-) mediated oxidation of hydroxyurea with H(2)O(2). Kinetic and mechanistic investigation

Dalton Trans. 2010 Feb 21;39(7):1695-8. doi: 10.1039/b920839a. Epub 2009 Dec 15.

Abstract

Reported in this paper is the first example of a ruthenium complex, [Ru(III)(edta)(H(2)O)](-) (edta = ethylenediaminetetra-acetate), that catalyzes the oxidation of hydroxyurea in the presence of H(2)O(2), mimicking the action of peroxidase or catalase and shedding light on their possible mechanism of action.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalase / chemistry*
  • Catalase / metabolism
  • Catalysis
  • Hydrogen Peroxide / chemistry*
  • Hydroxyurea / chemistry*
  • Kinetics
  • Oxidation-Reduction
  • Peroxidase / chemistry*
  • Peroxidase / metabolism
  • Ruthenium / chemistry*

Substances

  • Ruthenium
  • Hydrogen Peroxide
  • Catalase
  • Peroxidase
  • Hydroxyurea