Prevalence and determinant factors of sarcopenia in patients with type 2 diabetes: the Korean Sarcopenic Obesity Study (KSOS)

Diabetes Care. 2010 Jul;33(7):1497-9. doi: 10.2337/dc09-2310. Epub 2010 Apr 22.

Abstract

Objective: We examined prevalence of sarcopenia in Korean patients with type 2 diabetes and compared body compositional parameters between subjects with and without type 2 diabetes.

Research design and methods: The Korean Sarcopenic Obesity Study (KSOS) included 810 subjects (414 patients with diabetes and 396 control subjects) who were examined using dual-energy X-ray absorptiometry. Prevalence of sarcopenia was defined using the skeletal muscle index (SMI).

Results: Prevalence in patients with diabetes and in the control group was 15.7 and 6.9%, respectively. In both men and women, SMI values were significantly decreased in patients with diabetes compared with subjects without diabetes. Furthermore, multiple logistic regression analysis showed that type 2 diabetes was independently associated with sarcopenia.

Conclusions: Type 2 diabetes was associated with increased risk of sarcopenia. These characteristics may contribute to physical disability and metabolic disorders in older adults with diabetes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon
  • Adult
  • Aged
  • Aged, 80 and over
  • Asian People / statistics & numerical data*
  • Body Composition
  • Diabetes Mellitus, Type 2 / ethnology*
  • Female
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Muscle, Skeletal
  • Obesity / diagnostic imaging
  • Obesity / ethnology*
  • Prevalence
  • Republic of Korea / epidemiology
  • Risk Factors
  • Sarcopenia / ethnology*
  • Young Adult