Antiaggressive activity of antibodies to S-100 protein in ultralow doses
Bull Exp Biol Med. 2009 Sep;148(3):527-9.
doi: 10.1007/s10517-010-0755-0.
[Article in
English,
Russian]
Affiliation
- 1 Materia Medica Holding Research-and-Production Company, Moscow.
Abstract
Experiments on rats demonstrated antiaggressive activity of ultralow doses of antibodies to S-100 protein in tests of motivated and unmotivated aggression. The effect of ultralow doses of antibodies to S-100 protein in single and course treatment was not inferior to that of benzodiazepine anxiolytic diazepam.
MeSH terms
-
Aggression / drug effects*
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Animals
-
Anti-Anxiety Agents / therapeutic use*
-
Antibodies / immunology*
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Antibodies / therapeutic use*
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Behavior, Animal / drug effects
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Diazepam / therapeutic use*
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Male
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Rats
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S100 Proteins / immunology*
Substances
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Anti-Anxiety Agents
-
Antibodies
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S100 Proteins
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Diazepam