Near infrared-fluorescent and magnetic resonance imaging molecular probe with high T1 relaxivity for in vivo multimodal imaging

Chem Commun (Camb). 2010 Jun 7;46(21):3705-7. doi: 10.1039/c000536c. Epub 2010 Apr 13.

Abstract

A new gadolinium chelating NIR fluorescent molecular probe increases T(1) relaxivity of water protons, facilitating combined optical and magnetic resonance imaging.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Animals
  • Chelating Agents / chemistry
  • Fluorescent Dyes / chemistry*
  • Gadolinium / chemistry
  • Magnetic Resonance Imaging*
  • Mice
  • Molecular Probes / chemistry*
  • Temperature

Substances

  • Chelating Agents
  • Fluorescent Dyes
  • Molecular Probes
  • Gadolinium