Is pure laparoscopic radical cystectomy still an attractive solution for the treatment of muscle-invasive bladder cancer?

Urol Int. 2010;85(3):291-5. doi: 10.1159/000310349. Epub 2010 Apr 8.

Abstract

Objective: The aim of this study is to report our experience with laparoscopic radical cystectomy (LRC), evaluating the technique and perioperative and pathological outcomes.

Methods: 47 LRCs were performed due to muscle-invasive bladder cancer. Conduits were performed in 23 patients and neobladders in 23 (one bi-intestinal). One ureterocutaneostomy was created.

Results: In 43 patients LRC was performed with minilaparotomy for urinary diversion. The mean operation time was 290 min. Four operations were converted. Complications included sigmoid colon injury, urinary leak, lymphatic leak, short-term paralytic ileus, and heart attack. Mean blood loss was 220 ml. Hospitalization time was 6 days. Tumor stage was pT2b, pT3a, pT3b, and pT4a in 28, 13, 5, and 1 patient, respectively. No positive margins were found. The mean number of lymph nodules was 17, while in the last 25 procedures it was 21. 17% of patients had tumor in the lymph nodes. The mean follow-up was 10 months. Local recurrence and dissemination was observed in 2%. Continence in patients receiving neobladder was fully satisfactory.

Conclusions: More complications are related to neobladder than to ileac conduit. LRC with minilaparotomy seems to be an attractive treatment option for patients with muscle-invasive bladder cancer. Radical cystectomy performed intracorporeally could be reserved for 'robot-assisted' operations.

MeSH terms

  • Aged
  • Cystectomy / methods*
  • Female
  • Hospitalization
  • Humans
  • Laparoscopy / methods*
  • Lymph Nodes / pathology
  • Male
  • Medical Oncology / methods
  • Middle Aged
  • Muscles / pathology
  • Neoplasm Invasiveness
  • Recurrence
  • Surgical Procedures, Operative
  • Time Factors
  • Treatment Outcome
  • Urinary Bladder / pathology
  • Urinary Bladder Neoplasms / diagnosis
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / surgery*
  • Urology / methods