Omission mismatch negativity builds up late

Neuroreport. 2010 May 12;21(7):537-41. doi: 10.1097/WNR.0b013e3283398094.

Abstract

The mismatch negativity (MMN) event-related potential (ERP) is elicited by irregular sounds in a regular sound sequence. MMN depends on the length of the preceding regular stimulation: in repetitive sequences, changes following only two or three repetitions may elicit MMN. Thus, MMN builds up rapidly. Infrequent omissions in a repetitive sound sequence may also elicit an MMN-like waveform. In this study, the build-up of this omission-related ERP was investigated. Trains of two to nine tones with omissions at the penultimate stimulus positions were presented. Results showed no consistent omission-related ERP. In contrast, when omissions occurred with 9% probability among continuously presented tones, the omission-related waveform was elicited. Thus, the omission-related ERP builds up later than MMN.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustic Stimulation
  • Adult
  • Auditory Cortex / physiology*
  • Auditory Perception / physiology*
  • Evoked Potentials, Auditory / physiology*
  • Female
  • Humans
  • Male
  • Signal Processing, Computer-Assisted
  • Young Adult