Towards MRI microarrays

Chem Commun (Camb). 2010 Apr 14;46(14):2420-2. doi: 10.1039/b925020d. Epub 2010 Jan 26.

Abstract

Superparamagnetic iron oxide nanometre scale particles have been utilised as contrast agents to image staked target binding oligonucleotide arrays using MRI to correlate the signal intensity and T(2)* relaxation times in different NMR fluids.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Contrast Media / chemistry*
  • DNA / chemistry
  • Ferric Compounds / chemistry
  • Magnetic Resonance Imaging / methods*
  • Magnetics
  • Metal Nanoparticles / chemistry
  • Oligonucleotide Array Sequence Analysis*

Substances

  • Contrast Media
  • Ferric Compounds
  • ferric oxide
  • DNA