Simulated surgery for a patient with neurofibromatosis type-1 who had severe cervicothoracic kyphoscoliosis and an anomalous vertebral artery

Spine (Phila Pa 1976). 2010 Apr 20;35(9):E368-73. doi: 10.1097/BRS.0b013e3181c42559.

Abstract

Study design: Case report.

Objective: To describe the usefulness of simulated surgery for evaluation of a patient with neurofibromatosis type-1 (NF-1) who had severe cervicothoracic kyphoscoliosis and an anomalous vertebral artery (VA).

Summary of background data: Several surgical procedures have been used in the treatment of cervicothoracic kyphoscoliosis associated with myelopathy in patients with NF-1. However, to our knowledge, there has been no report that describes a surgical procedure for NF-1 patients with anomalous VA at the cervical spine.

Methods: A 45-year-old man with NF-1 developed cervical myelopathy. Preoperative examinations revealed severe cervicothoracic kyphoscoliosis, dystrophic changes of the cervical vertebrae, and the anomalous course of a VA and VA aneurysms. To assist in the preoperative planning and intraoperative navigation, we created 3-dimensional (3D) full-scale models of the patient's spine. Using a model, we performed a simulation of the planned surgery for spinal cord decompression with spinal fusion through both anterior and posterior approaches.

Results: Through the simulation, we could evaluate the risk of VA injury at the process of corpectomy, and altered the surgical procedure for the spinal cord decompression with spinal fusion from a posterior approach and a bone graft alone from an anterior approach. We accomplished the surgery successfully without any neurovascular complications. After surgery, the patient experienced relief from myelopathy.

Conclusion: Preoperative surgical simulation using a 3D full-scale model was useful for improving the accuracy and safety of the surgery for cervicothoracic kyphoscoliosis with NF-1.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cervical Vertebrae / diagnostic imaging
  • Cervical Vertebrae / surgery*
  • Computer Simulation*
  • Humans
  • Kyphosis / complications
  • Kyphosis / diagnostic imaging
  • Kyphosis / surgery*
  • Laminectomy
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Models, Anatomic*
  • Neurofibromatosis 1 / complications
  • Neurofibromatosis 1 / diagnostic imaging
  • Neurofibromatosis 1 / surgery*
  • Radiography
  • Scoliosis / complications
  • Scoliosis / diagnostic imaging
  • Scoliosis / surgery*
  • Spinal Fusion
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / surgery*
  • Treatment Outcome
  • Vertebral Artery / abnormalities
  • Vertebral Artery / diagnostic imaging
  • Vertebral Artery / surgery*