[The relationship between the abnormal behavior and serum C-reactive protein in children with obstructive sleep apnea-hypopnea syndrome]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Dec;23(24):1120-2.
[Article in Chinese]

Abstract

Objective: To explore the pathogenesis of abnormal behavior in children with obstructive sleep apnea-hypopnea syndrome (OSAHS).

Method: The behavioral problems and C-reactive protein were measured in 40 children with OSAHS and 30 children with habitual snoring who underwent overnight Polysomnography, 40 cases of healthy children for the control group.

Result: The ratio of abnormal behavior in OSAHS and habitual snoring children was significantly higher than that of the healthy control group, while no significant difference between the two groups. The content of C-reactive protein in OSAHS children (4.24 mg/L) was significantly higher than habitual snoring (2.76 mg/L) and healthy control group (1.27 mg/L); in habitual snoring children C-reactive protein was higher than in healthy control group. The content of serum C-reactive protein in OSAHS children accompanied by abnormal behavior (4.63 mg/L) was significantly higher than that without abnormal behavior (3.23 mg/L). The content of serum C-reactive protein content in habitual snoring children accompanied by abnormal behavior (3.63 mg/L) was significantly higher than that without abnormal behavior (1.76 mg/L).

Conclusion: OSAHS and habitual snoring children have more behavior problems. C-reactive protein levels are higher in children with OSAHS and habitual snoring, and the levels of C-reactive protein are related to the abnormal behavior in these children.

Publication types

  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • C-Reactive Protein / analysis*
  • Child
  • Child Behavior Disorders / complications*
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Polysomnography
  • Sleep Apnea, Obstructive / blood*
  • Sleep Apnea, Obstructive / complications
  • Sleep Apnea, Obstructive / psychology*
  • Snoring / blood
  • Snoring / complications
  • Snoring / psychology

Substances

  • C-Reactive Protein