Intraventricular amphotericin for absidiomycosis in an immunocompetent child

Hong Kong Med J. 2010 Apr;16(2):137-40.

Abstract

Brain abscesses are uncommon in children. We report a 3-year-old, previously healthy and immunocompetent boy, with an Absidia brain abscess. He presented with decreased sensorium and status epilepticus. The brain abscess was detected using cranial computed tomography and magnetic resonance imaging, and the diagnosis was confirmed with pus and brain tissue cultures. The patient responded to surgical drainage with concomitant intravenous and intraventricular amphotericin B.

Publication types

  • Case Reports

MeSH terms

  • Absidia / isolation & purification
  • Amphotericin B / administration & dosage
  • Amphotericin B / therapeutic use*
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use
  • Brain Abscess / diagnosis
  • Brain Abscess / microbiology
  • Brain Abscess / therapy*
  • Child, Preschool
  • Drainage / methods
  • Humans
  • Immunocompetence
  • Injections, Intraventricular
  • Male
  • Mucormycosis / drug therapy*
  • Mucormycosis / microbiology

Substances

  • Antifungal Agents
  • Amphotericin B