Abstract
Genitourinary tuberculosis was diagnosed in 543 patients in Spanish hospital from 1978 through 2003. Of the 371 male 34 (9.2%) had orchiepididymitis. Mean age was 52.7 years and the presenting symptom was scrotal swelling and/or pain. Over 50% of cases involved the right ovotestis. Associated renal tuberculosis and active disease in extraurological organs presented in 64% and 19.2% of cases, respectively. Diagnosis was established by culture of Mycobacterium tuberculosis recovery from urine and/or purulent scrotal exudate. Genomic amplification techniques aided the diagnosis in 8 patients. Treatment was rifampin, isoniazide, and pyrazinamide or ethambutol. Eight patients required combined medical and surgical treatment.
Copyright © 2010 Elsevier Inc. All rights reserved.
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Antitubercular Agents / therapeutic use
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Combined Modality Therapy
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Comorbidity
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Epididymitis / diagnosis
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Epididymitis / drug therapy
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Epididymitis / epidemiology*
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Epididymitis / microbiology
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Epididymitis / surgery
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Ethambutol / therapeutic use
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Exudates and Transudates / microbiology
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HIV Infections / epidemiology
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Humans
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Isoniazid / therapeutic use
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Male
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Middle Aged
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Mycobacterium tuberculosis / classification
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Mycobacterium tuberculosis / genetics
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Mycobacterium tuberculosis / isolation & purification*
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Orchitis / diagnosis
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Orchitis / drug therapy
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Orchitis / epidemiology*
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Orchitis / microbiology
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Orchitis / surgery
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Prostatitis / drug therapy
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Prostatitis / epidemiology
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Prostatitis / microbiology
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Pyrazinamide / therapeutic use
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RNA, Ribosomal, 16S / genetics*
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Retrospective Studies
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Ribotyping*
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Rifampin / therapeutic use
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Scrotum / microbiology
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Spain / epidemiology
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Tuberculosis, Male Genital / diagnosis
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Tuberculosis, Male Genital / drug therapy
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Tuberculosis, Male Genital / epidemiology*
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Tuberculosis, Male Genital / microbiology
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Tuberculosis, Male Genital / surgery
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Tuberculosis, Renal / epidemiology
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Urine / microbiology
Substances
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Antitubercular Agents
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RNA, Ribosomal, 16S
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Pyrazinamide
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Ethambutol
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Isoniazid
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Rifampin