The prognostic role of uterine artery Doppler investigation in patients with severe early-onset preeclampsia

Am J Obstet Gynecol. 2010 Jun;202(6):559.e1-4. doi: 10.1016/j.ajog.2010.01.048. Epub 2010 Mar 29.

Abstract

Objective: The purpose of this study was to evaluate the prediction capacity of uterine artery Doppler investigation for maternal and neonatal complications in women who are admitted with severe early-onset preeclampsia.

Study design: A uterine artery Doppler examination was performed at admission for patients with severe early-onset (<34 weeks of gestation) preeclampsia. The maternal and neonatal outcome of women with abnormal uterine Doppler results was compared with those with normal Doppler results.

Results: One hundred twenty patients were included. In 53% of them, uterine Doppler results were abnormal. This group had a lower gestational age at delivery (30.2 vs 32.7 weeks; P < .001) and a higher proportion of small-for-gestational age infants (87.5% vs 67.9%; P = .009). Neonatal (40.6% vs 14.3%; P = .01) and maternal (28.1% vs 5.4%; P = .001) complications were more common in the abnormal uterine Doppler group.

Conclusion: Women with severe early-onset preeclampsia are at higher risk of maternal and neonatal complications if abnormal uterine blood flow is present.

MeSH terms

  • Adult
  • Blood Flow Velocity
  • Female
  • Gestational Age
  • Humans
  • Patient Selection
  • Pre-Eclampsia / diagnostic imaging*
  • Pregnancy
  • Prognosis
  • Regression Analysis
  • Ultrasonography, Prenatal
  • Uterine Artery / diagnostic imaging*