[Adenosine deaminase activity in hepatomas of varying degrees of malignancy]

Biull Eksp Biol Med. 1978 Jan;85(1):60-1.
[Article in Russian]

Abstract

In highly malignant Gelshtein 22A hepatcma and ascites Ehrlich carcinoma adenosine deaminase activity was found to be reduced 3-fold as compared with that of the normal mouse liver. In less malignant hepatomas adenosine deaminase activity drops only by 20%. A certain reduction of adenosine deaminase activity was also noted in the liver to tumour-bearing mice.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adenosine Deaminase / metabolism*
  • Animals
  • Carcinoma, Ehrlich Tumor / enzymology
  • Carcinoma, Hepatocellular / enzymology*
  • Enzyme Activation
  • Liver / enzymology
  • Liver Neoplasms / enzymology*
  • Mice
  • Mice, Inbred C3H
  • Neoplasm Transplantation
  • Neoplasms, Experimental / enzymology
  • Nucleoside Deaminases / metabolism*

Substances

  • Nucleoside Deaminases
  • Adenosine Deaminase