Abstract
Six selaginellin derivatives, including three new analogues selaginellins D-F (1-3), were isolated from the EtOAc extract of the whole plant of Selaginella pulvinata (Hook. et Grev.) Maxim. Their structures were determined on the basis of extensive physical and chemical evidence. Compounds 1 and 4 demonstrated antifungal activities against Candida albicans; compounds 4-6 exhibited significant antibacterial activity against Staphylococcus aureus.
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MeSH terms
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / isolation & purification*
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Anti-Infective Agents / pharmacology
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Benzhydryl Compounds / chemistry
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Benzhydryl Compounds / isolation & purification*
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Benzhydryl Compounds / pharmacology
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Candida albicans / drug effects
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Cyclohexanones / chemistry
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Cyclohexanones / isolation & purification*
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Cyclohexanones / pharmacology
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Models, Molecular
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Plant Extracts / pharmacology*
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Selaginellaceae / chemistry*
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Staphylococcus aureus / drug effects
Substances
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Anti-Infective Agents
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Benzhydryl Compounds
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Cyclohexanones
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Plant Extracts