The administration of transcranial electric treatment for affective disturbances therapy in alcoholic patients

Drug Alcohol Depend. 1991 Jan;27(1):1-6. doi: 10.1016/0376-8716(91)90080-i.

Abstract

In a double blind placebo-controlled investigation it was shown that transcranial electric treatment (TET), comprising the combination of a constant current with a pulse current of square impulses of 70-80 Hz is an effective method to correct affective disturbances (anxiety, depression) in alcoholic patients. The medical effects of TET are accompanied by changes in the metabolism of GABA and monoamines, but not of beta-endorphin, and also by a decrease in the latency of alpha-rhythm appearance after closing of the eyes.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Alcoholism / enzymology
  • Alcoholism / psychology
  • Alcoholism / rehabilitation*
  • Alpha Rhythm
  • Anxiety Disorders / enzymology
  • Anxiety Disorders / psychology
  • Anxiety Disorders / rehabilitation*
  • Arousal / physiology
  • Depressive Disorder / enzymology
  • Depressive Disorder / psychology
  • Depressive Disorder / rehabilitation*
  • Electric Stimulation Therapy / methods*
  • Ethanol / adverse effects*
  • Humans
  • Isoenzymes / blood
  • Monoamine Oxidase / blood
  • Personality Tests
  • Substance Withdrawal Syndrome / enzymology
  • Substance Withdrawal Syndrome / psychology
  • Substance Withdrawal Syndrome / rehabilitation*
  • gamma-Aminobutyric Acid / blood

Substances

  • Isoenzymes
  • Ethanol
  • gamma-Aminobutyric Acid
  • Monoamine Oxidase