New amide alkaloid from the aerial part of Piper capense L.f. (Piperaceae)

Fitoterapia. 2010 Sep;81(6):632-5. doi: 10.1016/j.fitote.2010.03.006. Epub 2010 Mar 20.

Abstract

Together with apigenine dimethylether and piperchabamide A, a new amide alkaloid, Kaousine and the Z form of antiepilepsirine were isolated from the aerial part of Piper capense L.f (Piperaceae). Their structures were elucidated by spectrometric methods and their in vitro antiparasitic activities were evaluated on Plasmodium falciparum.

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Amides / chemistry
  • Amides / isolation & purification*
  • Antimalarials / isolation & purification*
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Cell Line, Tumor
  • Epoxy Compounds / chemistry
  • Epoxy Compounds / isolation & purification*
  • Humans
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Piper / chemistry*
  • Piperidines / isolation & purification
  • Plant Extracts / chemistry
  • Plants, Medicinal / chemistry

Substances

  • Alkaloids
  • Amides
  • Antimalarials
  • Antineoplastic Agents, Phytogenic
  • Epoxy Compounds
  • Piperidines
  • Plant Extracts
  • kaousine
  • ilepcimide