Thirty years of heme peroxidase structural biology

Arch Biochem Biophys. 2010 Aug 1;500(1):3-12. doi: 10.1016/j.abb.2010.02.008. Epub 2010 Mar 3.

Abstract

The following is a brief review of peroxidase structural biology since the initial structure determination of cytochrome c peroxidase (CCP) 30 years ago. An emphasis will be placed on what CCP has taught us about peroxidase mechanisms, especially Compound I formation and electron transfer.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Crystallography, X-Ray
  • Cytochrome-c Peroxidase / chemistry
  • Cytochrome-c Peroxidase / metabolism
  • Electron Transport
  • Humans
  • Models, Molecular
  • Peroxidases / chemistry*
  • Peroxidases / metabolism*
  • Protein Conformation
  • Saccharomyces cerevisiae Proteins / chemistry
  • Saccharomyces cerevisiae Proteins / metabolism

Substances

  • Saccharomyces cerevisiae Proteins
  • Peroxidases
  • Cytochrome-c Peroxidase